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To Test Glutamate Hypothesis for Schizophrenia Utilizing Proton Magnetic Resonance Spectroscopy Sachiko Tsugawa 1 , Shin-ichiro Luke Nakajima 2 1Keio University School of Medicine 2Department of Neuropsychiatry, Keio University School of Medicine Keyword: 統合失調症 , グルタミン酸仮説 , 核磁気共鳴スペクトロスコピー , schizophrenia , glutamate hypothesis , magnetic resonance spectroscopy pp.1035-1040
Published Date 2017/9/1
DOI https://doi.org/10.11477/mf.1416200863
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Abstract

Recent advancement in magnetic resonance spectroscopy (MRS) has elucidated the pathophysiology of mental illness, including schizophrenia. MRS is a neuroimaging technique that non-invasively measures chemicals, using nuclear magnetic resonance. This narrative review explains proton MRS (1H-MRS) and introduces pivotal studies to examine a glutamate hypothesis for schizophrenia, employing 1H-MRS.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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