放射線併用動注化学療法後，膀胱全摘除術を施行した膀胱扁平上皮癌

Experience of Total Cystectomy after Radiation Therapy Combined with Intra-arterial Chemotherapy for Squamous Cell Carcinoma of the Urinary Blad-der : A Cace Report

　症例は52歳，男性。主訴は肉眼的血尿であった。IVPにて膀胱右側壁に陰影欠損を認め，CTおよびMRIにて腫瘍の壁外浸潤を認めた。経尿道的膀胱生検にて膀胱扁平上皮癌と診断した（T3b,N0,M0）。放射線併用動注（シスプラチン＋ドキソルビシン塩酸塩）療法を施行したのち，膀胱全摘除術および代用膀胱造設術を行ったところ，病理学的にCRであった。

A 52-year-old man was admitted to our hospital with a chief complaint of gross hematuria. IVP demonstrated a filling defect on the right bladder wall. CT scan and MRI suggested extravesical invasion of the tumor. Diagnosis of squamous cell carcinoma was made by transurethral biopsy (T3b, N0, M0) . The patient received intra-arterial chemotherapy (CDDP and ADM) combined with radia-tion. After second course of this therapy, radical cystectomy with ileal neobladder was performed. Pathological study revealed no tumor cells in the removed bladder (CR) .