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Japanese

Selective vesical arterial infusion as neoadjuvant chemotherapy for bladder tumor Takashi Tomemori 1 , Naohiro Terada 2 , Masahiro Sasaoka 3 , Tomio Araki 4 , Osamu Mori 4 , Hiroshi Nakano 5 , Kan Takeda 1 Keyword: 膀胱腫瘍 , 動注化学療法 pp.49-54
Published Date 2003/1/20
DOI https://doi.org/10.11477/mf.1413100771
  • Abstract
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To deliver a dense anticancer drug to tumor,we performed the selective vesical arterial drug infusion for 16 patients with bladder cancer.Anticancer drug was infused from bilateral vesical arteries in 8 patients,and from unilateral vesical artery in another 8 patients.In three of the eight patients with unilateral arterial infusion,the infusion was performed with the opposite internal iliac artery occluded by a balloon catheter.The therapeutic effect was evaluated by CT imaging before and after arterial infusion,and also by histopathological findings after cystectomy.There was no significant difference,but the tumor volume reduction rate assessed by CT imaging tended to be higher in the bilateral infusion group than in the unilateral infusion group.The side effects of the treatment were observed in all male patients,which were mild in severity and all patients recovered soon after infusion.Bilateral vesical arterial infusion chemotherapy is thought to be useful as neoadjuvant chemotherapy for bladder cancer without severe complication.


Copyright © 2003, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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