膀胱絨毛癌の1例

A Case Report of Primary Choriocarcinoma of the Urinary Bladder

　症例は62歳，男性。無症候性肉眼的血尿により受診した。膀胱鏡にて左後壁から側壁，頂部の広範囲にわたる非乳頭状，広基性の腫瘤を認めた。腹部超音波検査・CT・MRIにて膀胱腫瘍T3bN2MOと診断した。病理学的には，一部に移行上皮癌の成分を含む絨毛癌で，hCG染色陽性であった。経尿道的切除術ののち，methotrexate，etoposide，cisplatinによる全身化学療法を3コース行ったが，初診時より8か月後に死亡した。

A 62-year-old male was referred to us due to work up and treatment for bladder tumor. Cystoscopy revealed a large non-papilary, broad-based tumor. Transurethral resection was peformed which was not curable operation because of big and invasive tumor. By the finding of histological and immunohistochemical studies, the final diagnosis was choriocarcinoma of the urinary bladder. Three courses of chemotherapy consisted of methotrexate, etoposide, cis-platin were performed. Although after one course of che-motherapy serumβ-human chorionic gonadotropin par-tially responded, it relapsed immediately.