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EXPRESSION OF RAS ONCOGENE PRODUCT (RAS P21) IN PROSTATIC CANCER Hidenori Sumiya 1 , Koichiro Akakura 1 , Hideki Fuse 1 , Jun Shimazaki 1 , Osamu Matsuzaki 2 1Department of Urology, School of Medicine, Chiba University 2Department of Surgical Pathology, Teikyo University School of Medicine, Ichihara Hospital pp.703-705
Published Date 1987/8/20
DOI https://doi.org/10.11477/mf.1413204552
  • Abstract
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Expression of ras oncogene product (ras p21) was examined in normal prostate, benign prostatic hyper-trophy and prostatic cancer by ABC (avidin-biotin-complex immunoperoxidase) method, No staining was observed in normal prostate (3 cases) and benign prostatic hypertrophy (4 cases). In prostatic cancer 57.1% of the cases were positive: well differentiated adenocarcinoma; 0/2(0%), moderately differentiated; 5/11 (45. 5%), poorly differentiated; 7/8 (87.5%). It was concluded that ras oncogene was related with histological grade of prostatic carcinoma.


Copyright © 1987, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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