Cis-diamminedichloroplatinumにより一時寛解した睾丸腫瘍脳転移の1例

A CASE WITH BRAIN METASTATIC LESION FROM TESTICULAR TUMOR RESPONDED REMARKABLY TO CIS-DIAMMINEDICHLOROPLATINUM ADMINISTRATION

はじめに

　睾丸腫瘍（胎児性癌，一部絨毛上皮癌を含む）の脳転移巣に対し，cis-diamminedichloroplatinum（以下CDDPと略す）の単独投与が奏効した1例を経験したので報告する。

We reported 25 years old male patient, in whom cis-diamminedichloroplatinum was remarkably effective to brain metastatic lesion from right testicular tumor. He was refractory to conventional chemo-therapy (V.A.B.). Metastatic lesions were composed of embryonal carcinoma with choriocarcinoma.We concluded that tumor vessels had no blood brain barrier or less activity of blood brain barrier, so cis-diamminedichloroplatinum entered brain metastatic lesion.