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Do you need a 24-hour creatinine clearance when you perform chemotherapy for urothelial carcinoma? Shunsuke Sato 1 , Atsushi Takahashi 1 , Yoshiki Hiyama 1 , Teruhisa Uehara 1 , Akio Takayanagi 1 , Yoshio Takagi 1 1Department of Urology, Hakodate Goryoukaku Hospital Keyword: 腎機能 , 尿路上皮腫瘍 , 化学療法 pp.321-326
Published Date 2014/4/20
DOI https://doi.org/10.11477/mf.1413103554
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We investigated the need of a 24-hour creatinine clearance(24-hour Ccr)when we performed chemotherapy for urothelial carcinoma. From January 2006 to April 2009, 24 chemotherapy patients received total of 70 courses. We used a 24-hour Ccr, Cockcroft-Gault(C-G)equation and estimated GFR(eGFR)as evaluation methods of renal function. Our results demonstrated that A 24-hour Ccr was higher than C-G equation and eGFR in 70% and 90%, respectively. If both C-G equation and eGFR were more than 60 ml/min, a 24-hour Ccr was more than 60 ml/min in 95%. Therefore if both C-G equation and eGFR are more than 60 ml/min, we might omit a 24-hour Ccr.


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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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