Hemangiopericytomaについて

HEMANGIOPERICYTOMA

I．緒言

　Stout　＆　Murray^1）は1942年，691例の血管系腫瘍を集計したが，その中にZimmermann^2）の唱えた毛細血管のpericyteに由来すると思われる腫瘍9例に対してHelnangiopericytomaと命名した。さらにStout^3）は1949年に本腫瘍の25例を纒めて報告し，このものを従来の他の血管系腫瘍から別箇のものとして新しい概念を確立した。

　本腫瘍は皮膚のみならず，毛細血管の存するところ全身諸臓器に生じ得るもので，欧米諸国においては今日まで比較的多くの報告がみられるが本邦では少なく，いまなお比較的稀な疾患と考えられている。著者は最近顔面皮膚に発生した本腫瘍の1例を経験し，あわせて自験例を含めた本邦の31報告例^4）〜30）について若干の文献的考察を試みたのでここに報告する。

A 44-year-old male farmer had noticed a slightly itchy red papule on the left ala nasi since June of 1965 which enlarged gradually.

On his first visit in April, 1961, the tumor was reddish, hemispherical, relatively well mar-ginated, finger tip-sized and covered with grayish-white or dark brown crust on the center. In the peripheral part follicular openings were prominent and discharged sebum. The tumor had discharged hemorrhagic exudate several times. There were no subjective sensations The results of laboratory tests were all within normal limits. Histologic specimen showed. marked proliferation and dilatation of capillaries accompanied with irregular proliferation of oval or spindle-shaped tumor cells around the vessels. The nucleus of the tumor cell was spindle-shaped and vacuolar, but mitotic figure was rarely seen. The tumor cells were inter-mingled with reticular fibers. Under the diagnosis of hemangiopericytoma the tumor was resected and skin grafting was performed in July, 1961. No recurrence was noted.

Hemangiopericytoma was described by Stout and Murray in 1942, and has been regarded as a rather rare tumor In Japan, 31 cases were reported, including 21 cases of original tumor of the skin. Review of reported cases in Japan was performed, which proved 32% of malignancy which started at any age.