側頭骨原発低分化型腺癌の1例

Primary Adenocarcinoma in the Temporal Bone:A Case Report

　はじめに

　側頭骨腫瘍はまれな疾患であり特徴的な症状を欠くため早期発見は困難である。手術では解剖学的に制限を受け，また放射線での根治も難しく一般的には十分な治療成績があげられていない。今回われわれは，激しい疼痛と顔面神経麻痺を伴い，中頭蓋窩まで進展した側頭骨原発の低分化型腺癌を経験した。化学療法（5-FU＋THP-ADM＋CDDP）と放射線治療の同時併用療法を行い，疼痛は消失しComplete Response （CR）の治療効果が得られたので報告する。

In a 56-year-old female patient complaining of right otalgia, a tumor was demonstrated at the regions of the right temporal bone and subdural space on MRI and CT. Histological examination of biopsy specimen obtained from the external audi-tory canal revealed poorly differentiated adenocar-cinoma. Chemotherapy with 5-FU, THP-ADM and CDDP combined with radiotherapy was performed. The patient obtained complete response and has been alive with disease. Metastatic cervical lymph nodes and lung tumor appeared 14 months after discharge.