原発性抗リン脂質抗体症候群に網膜血管炎を合併した1例

A case of retinal vasculitis associated with primary antiphospholipid antibody syndrome

（展示235）　47歳女性の，原発性抗リン脂質抗体症候群の患者に，網膜血管炎が合併した症例を報告した。腓腹神経生検にて，器質化血栓周囲に炎症細胞浸潤を伴う血管症を認めた。眼底には網膜浮腫，硬性白斑，火炎状出血を認め，螢光眼底撮影における動脈に沿った螢光漏出と，組織染から網膜血管炎と診断した。網膜血管炎の病態も，腓腹神経生検の結果と同様に血栓に続発した二次的血管炎と推察した。

A 47-year-old female presented with blurring in the right eye of 20 day's duration. She had the past history of recurrent horizontal hemianopia in the right eye, paraplegia due to peripheral neuritis and cerebral infarction. Biopsy of sural nerve had shown vasculopathy with organized thrombosis surrounded by infiltration of phagocytes, leading to the diagnosis of primary antiphospholipid antibody syndrome (PAPS) . Funduscopy showed retinal edema, hard exudates and flame-shaped hemorrhages in the right eye. Fluorescein angiography showed leakage and dye staining along retinal arteries. The affected eye was diagnosed as retinal vasculitis presumably secondary to thrombus formation as a manifestation of PAPS.