超音波生体顕微鏡を用いたベーチェット病眼の観察

Ultrasound biomicroscopic findings in eyes of Behçet disease

（26C1-14）　ベーチェット病患者34例62眼の前眼部を，超音波生体顕微鏡（ultrasound biomicroscopy：UBM）を用いて観察した。眼発作後には輝度の高い点状反射像が前房，後房内にみられ，毛様体近傍の前部硝子体内には発作後4週以上経過した症例でも52.9％にみられた。反射像がある眼の視力は悪く，眼底スコアやフレア値も高く，要因として過去の発作回数の関与が考えられた。末期眼では組織の構築は不整で毛様体厚が厚く，前部硝子体内には網膜前肉芽組織を示唆する点状反射の集簇像や，毛様体脈絡膜浮腫性剥離と増殖性変化を示唆する反射像が得られた。

We examined the anterior segment of 62 eyes with Behçet disease using a high-frequency ultrasound biomicroscope, UBM. Immediately after ocular attacks, UBM showed punctate reflexes in the anterior chamber, posterior chamber and anterior vitreous. The findings were suggestive of presence of inflammatory cells. The punctate reflexes in the anterior vitreous were still present in 53% of eyes four weeks after ocular attacks. Eyes with punctate reflexes in the vitreous showed poorer visual acuity, more intense aqueous flare and higher fundus scores. Eyes in the terminal stage of the disease showed irregular structure of intraocular tissues, thickened ciliary body, clusters of reflexes suggesting granulation in the anterior vitreous, ciliary detachment, or intraocular proliferation.