A bilateral case of mucosa-associated lymphoid tissue (MALT) lymphoma in the conjunctiva Hiroshi Takebayashi 1 , Toshiro Sakuma 1 , Minoru Tanaka 1 , Masaaki Noguchi 2 , Kazuhisa Ishi 3 , Fujihiko Suzuki 3 1Dept of Ophthalmol, Urayasu Hosp, Juntendo Univ 2Dept of Hematol, Urayasu Hosp, Juntendo Univ 3Dept of Med Technol, Urayasu Hosp, Juntendo Univ pp.1073-1076
Published Date 2002/6/15
DOI https://doi.org/10.11477/mf.1410907786
  • Abstract
  • Look Inside

A 32-year-old male was referred to us for suspected inflammatory pseudotumor in the left orbit. He showed salmon-pink tumors in the bulbar and palpebral conjunctiva in the left eye. Biopsy showed diffuse malignant lymphoma of small cell type. Immunohistologically, the tumor cells were positive for L-26 and κ stain and negative for UCHL and λ stain. Flow cytometry showed high positivity for κ chain, CD19 and CD20. Molecular analysis by Southern blot hybridization showed rearrangement of immunoglobulin heavy chain band. These findings led to the diag-nosis of mucosa-associated lymphoid tissue (MALT) lymphoma. A similar lesion developed in the right eye 4 months later. The tumors disappeared following radiation with electron beams totalling 30 Gy right and 38 Gy left. There has been no local recurrence or metastasis during one year's follow up.

Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院