Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
複数の点眼薬を使用中の原発開放隅角緑内障11例21眼にラタノプロスト点眼を行った。2剤を使用中の10眼をラタノプロスト単独点眼としたとき,眼圧が変更前20.2±1.4mmHg,変更後17.5±4.9mmHgとなり,有意に下降した(p=0.04)。3剤を使用中の11眼をラタノプロストとβ遮断薬の2剤併用にしたとき,眼圧が変更前17.2±2.8mmHg,変更後17.2±4.0mmHgとなり,有意差がなかった。使用する点眼薬数を減らしても,それ以前と同等以上の眼圧下降が得られ,コンプライアンス向上に寄与したと評価される。
We used topical latanoprost in 21 eyes of 11 patients of primary open-angle glaucoma. They had been us-ing multiple topical medications before. Ten eyes had been treated by two medications. After switching to latanoprost only, the intraocular pressure (IOP) averaged 20.2±1.4mmHg before and 17.5±4.9mmHg after switching. The dif-ference was significant (p=0.04). Eleven eyes had been treated by three medications. After switching to latanoprost and beta-blocker, the IOP averaged 17.2±2.8mmHg before and 17.2±4.0mmHg after switching. There was no sig-nificant difference. The findings show that reduction in the number of topical medications by latanoprost may result in good IOP control contributing to improved compliance.
Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.