抗lipoarabinomannan-B抗体陽性ぶどう膜炎患者の臨床像

Clinical features of anti-lipoarabinomannan-B antibody positive uveitis

　ぶどう膜炎患者25例に対し，抗酸菌の共通抗原であるipoarabinornannan-Bに対する抗体価をELISA法で測定した。陽性は6例であり，内訳はベーチェット病が1例，サルコイドーシス1例，イールズ病1例，原因不明3例であった。このうち全身的に抗酸菌感染を疑わせる例はイールズ病と原因不明例の計2例であった。抗体陽性例に特徴的なぶどう膜炎の臨床所見はなかった。

We quantitated the serum titer for anti-lipoarabinomannan-B antibody, a glycoprotein of Mycobacterium cell walls, in 25 uveitis patients. An ELISA method was used in the quantitation. It was positive in 6 patients, including Behçet disease 1, sarcoidosis 1, Eales disease 1 and unknown uveitis 3 cases. Systemic signs of Mycobacterium infection were present in 2 cases, including one case each of Eales disease and unknown uveitis. None of the 6 cases showed features of uveitis which appeared to be characteristic for the presence of anti-lipoarabinomannan-B antibody.