Japanese

Clinical features of thirteen cases with toxoplasmic retinochoroiditis Mari Kusakabe 1,2 , Toshikatsu Kaburaki 2,3 , Rie Tanaka 2 , Kazuyoshi Ohtomo 4 , Mitsuko Takamoto 5 , Hisae Nakahara 2 , Kimiko Okinaga 5 , Shintaro Shirahama 2 , Jiro Numaga 6 , Yujiro Fujino 4 , Makoto Aihara 2 1Department of Ophthalmology, JCHO Tokyo Yamate Medical Center 2Department of Ophthalmology, The University of Tokyo Hospital 3Department of Ophthalmology, Jichi Medical University Saitama Medical Center 4Department of Ophthalmology, JCHO Tokyo Shinjuku Medical Center 5Department of Ophthalmology, Saitama Red Cross Hospital 6Department of Ophthalmology, Tokyo Metropolitan Geriatric Hospital pp.395-404
Published Date 2020/4/15
DOI https://doi.org/10.11477/mf.1410213517
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Abstract Purpose:To report clinical features of 13 cases with toxoplasmic retinochoroiditis.

Cases:We observed 13 cases of toxoplasmic retinochoroiditis during 19 years through 2019 at University of Tokyo Hospital. The series comprised 9 males and 4 females. It was unilateral in 12 cases and bilateral in one. It was congenital in 2 cases, acquired in 9 eyes of 8 cases, and was uncertain in 3 cases. Age of onset was 17.5 years, 44.9 years, and 61.1 years respectively. Only the macula was involved in congenital cases. The macula was involved in 4 and the peripheral fundus was involved in 5 of acquired cases. Only the peripheral fundus was involved in uncertain cases. All cases were treated by peroral acetylspiramycin. Seven cases received, additionally, prednisolone. Recurrence occurred in 4 cases, including 3 cases of macular and one case of peripheral involvement.

Conclusion:Toxoplasmic retinochoroiditis in the present series was characterized by unilateral involvement, preponderance of acquired than congenital origin, and more frequent involvement of peripheral fundus in acquired cases. Systemic treatment with acetylspiramycin was safe and effective in the majority of cases.


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