ICG螢光造影による加齢性黄斑変性の脈絡膜新生血管分類とその視力予後

Classification and visual outcome of choroidal neovascularization in age-related macular degeneration by indocyanine green angiography

（18-D501-4）　フルオレセイン螢光造影で，隠れた脈絡膜新生血管を有した加齢性黄斑変性症例109例122眼（年齢50〜91歳，平均69.1±9.4歳）のインドシアニングリーン螢光造影所見を，Guyerらの分類にしたがって過螢光部の大きさから，focal spots, plaquesおよび両者が混在するcombination lesionsに分類した。各分類の頻度は，focal spots 39眼（32％），plaques 67眼（55％），combination lesions11眼（9％）で，Guyerらの報告とほぼ一致した。1年以上の自然経過群と光凝固術実施群において，各分類の視力予後，光凝固術の成績を検討したが，各分類間に統計学的な有意差はなかった。視力予後には新生血管の位置や活動性（activity）が影響した。

We reviewed 122 eyes with age-related macular degeneration showing occult choroidal neovascularization by fluorescein angiography. The 109 patients were aged from 50 to 91 years, average 69 years. The choroidal neovasculariza-tion was classified into three types by indocyanine green angiographic features : focal spots 39 eyes (32%) , plaques 67 eyes (55%) and combined lesions 11 eyes (9%) . The frequency was similar to that by Guyer et al. There was no difference in the natural history and results of photocoagulation among the 3 groups after follow up for 1 year or longer. It appeared that the visual outcome is more influenced by the location and activity of the underlying choroidal neovascularization.