マイトマイシンCを用いた翼状片手術による治療成績

The new pterigium treatment with mitomycin C

　翼状片手術中にマイトマイシンC （以下MMC）を用いる方法を考え，A, Bの2施設で手術を行い，術後6か月以上経過観察した45例47眼の結果を報告した。A施設では結膜弁移植法を行い，翼状片組織を除去後，露出した強膜上に0.02mgMMCを浸したMQAの切片を3分間付着させ，生理食塩水50mlで洗い流し，結膜弁を移植した。B施設では強膜露出法を行い，同様に強膜上にMQAの切片を5分間付着させ，生理食塩水250mlで洗い流した。結果として，再発眼はB施設の1眼のみで，MMC使用による合併症は，全く見られなかった。本方法は，簡便かつ安全で，再発予防に有用なため，今後活用すべき手術方法と思われた。

We evaluated the pterigium treatment with mitomycin C in 45 cases of the 47 eyes. We selected 2 types of operative procedure. The first was the conjunctival graft methods. Briefly, after pterigium removal, we attached a piece of MQA on the ex-plosured sclera that was treated with 0.02 mg mitomycin for 3 minutes and washed by 50 ml saline and then transplanted the conjunctival graft at Ikoma General Hospital. The second was the bare sclera exposure after pterigium removal with same dose mitomycin for 5 minutes and washed by 250 ml saline at Nagata Eye Clinic. Recurrence was noted only one eye at the latter. There were no complication in both. The result suggested that these procedures were safe and efficient to prevent recurrence.