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Problems and proposals about indocyanine fluorescence angiography Shin Yoneya 1 , Kimiharu Noyori 1 , Koichi Shimizu 2 1Dept of Ophthalmol, Saitama Med Sch 2Dept of Ophthalmol, Gunma Univ Sch of Med pp.549-552
Published Date 1993/3/15
DOI https://doi.org/10.11477/mf.1410901563
  • Abstract
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We performed fluorescence angiography in pig-mented rabbits using conventional ICG solution and ICG previously conjugated with albumin. Fluores-cence in the choroid was well observed 6 seconds after administration of modified ICG. Appearanceof fluorescence in the fundus was slow and fainter with conventional ICG solution. In vitro experi-ments showed that free ICG showed maximum fluorescence 60 seconds after binding with albumin. This fact seemed to underlie the observed superior-ity of protein-bound ICG over aqueous ICG during fluorescence angiography.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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