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Japanese

Oral itraconazole was effective in two cases of Acantha moeba keratitis Yasuhisa Ishibashi 1 , Ryoko Watanabe 1 , Takamichi Kabata 1 , Sachiko Hommura 1 , Kazuo Yasuraoka 2 , Keiichi Ishii 3 1Dept of Ophthalmol, Univ of Tsukuba 2Dept of Parasitol, Univ of Tsukuba 3Dept of Biol, Hosei Univ pp.551-555
Published Date 1990/4/15
DOI https://doi.org/10.11477/mf.1410900138
  • Abstract
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We treated 2 female patients of Acanthamoeba keratitis, aged 19 and 37 years, with oral itracon-azole, topical miconazole and surgical debridementof the lesion. Regression started 7 days after initia-tion of treatment. The clinical signs of corneal infection disappeared after 5 and 8 weeks respec-tively. The visual acuity improved from counting fingers to 1.2 and from hand movement to 0.5 each. No systemic or topical signs of toxicity or adverse reactions were observed throughout the course of treatment.


Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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