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Acanthamoeba keratitis in a contact lens non -wearer Takamichi Kabata 1 , Yasuhisa Ishibashi 2 , Sachiko Hommura 2 , Youziro Matsumoto 3 , Keiichi Ishii 4 1Dept of Ophthalmol, Univ Hosp of Tsukuba 2Dept of Ophthalmol, Inst of Clin Medi Univ of Tsukuba 4Dept of Biology, Hosei Univ pp.93-97
Published Date 1992/1/15
DOI https://doi.org/10.11477/mf.1410900996
  • Abstract
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A 39-year-old man developed corneal infection simulating disciform keratitis. He underwent treat-ment with antiviral agents and corticosteroid under the tentative diagnosis of herpetic keratitis. He was referred to us due to exacerbation after 4 months of treatment. Cytological studies of biopsied corneashowed Acanthamoeba with ink-potassium hydro-xide staining. Cultured scraping materials yielded Acanthamoeba culbertsoni, which has not as yet been identified from Acanthamoeba keratitis in Japan. He was then treated with oral fluconazole, topical miconazole and surgical debridement of corneal lesion. These treatments were effective and were well-tolerated. This case is, to our best know-ledge, the first reported one of Acanthamoeba keratitis in contact lens non-wearer in Japan. This patient presumably suffered from mild corneal injury and was exposed to contaminated soil prior to manifest corneal infection.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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