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要約 目的:前眼部光干渉断層装置CASIA2の応用によって生体における水晶体の形態解析が可能となった。白内障手術症例における水晶体の傾斜と偏心について報告する。
対象と方法:はなみずき眼科において,白内障手術連続症例120例230眼(平均年齢73.2±8.4歳)を検討した。術前視力,眼圧,等価球面,眼軸長(OA-2000,Tomey)を計測した。また,CASIA2(Tomey)は白内障術前モードにて撮影し,前房深度,前房幅,水晶体厚,水晶体の傾斜と偏心を計測した。水晶体の傾斜と偏心への関与因子について多変量相関解析(JMP ver. 14)を行った。
結果:男性54例102眼,女性66例118眼を検討した。性差は,眼軸において男性が有意に長かった(p=0.015)。水晶体の平均傾斜は4.6±1.5°で,方位は231.1±98.7°であった。傾斜は年齢と有意に正の相関(Spearman's rank correlation coefficient r=0.211,p=0.034),眼軸長と負の相関(r=−0.3475,p=0.004)を示した。水晶体の平均偏心は0.15±0.08mmで,方位は188.9±100.4°であった。偏心は年齢と有意に正の相関(r=0.2401,p=0.016),前房深度と負の相関(r=−0.222,p=0.025)を示した。傾斜度と偏心量とが有意に正の相関を示した(r=0.451,p<0.001)。
結論:CASIA2による水晶体の形態解析が可能であった。水晶体の傾斜と偏心は加齢によって増加する一方,眼軸長および前房深度にも相関する可能性を示唆した。
Abstract Purpose:The second-generation anterior segment optical coherence tomography(OCT)CASIA2 is capable of measuring the in vivo crystalline lens. We investigated the tilt and decentration of crystalline lens of patients scheduled for cataract surgery.
Subjects and Methods:Two-hundred thirty eyes of 120 patients(mean age, 73.2±8.4 years)scheduled for cataract surgery in Hanamizuki Eye Clinic were studied. Visual acuity, intraocular pressure, equivalent spherical, ocular length(OA-2000, Tomey)were examined before and 1 month after surgery. CASIA2(Tomey)was used to measure the anterior chamber depth(ACD), anterior chamber width, lens thickness, lens tilt and decentration. Factors related to lens tilt and decentration were analyzed using multivariate analyses(JMP ver. 14).
Results:One-hundred and two eyes of 54 males and 118 eyes of 66 females were studied. The ocular length was significantly longer for males than females(p=0.015). The average tilt of lens was 4.6±1.5 degrees with an azimuth of 231.1±98.7 degrees. Lens tilt was significantly and positively correlated with age(Spearman correlation coefficient r=0.211, p=0.034), and was negatively correlated with ocular length(r=−0.3475, p=0.004). The average decentration of lens was 0.15±0.08 mm with an azimuth of 188.9±100.4 degrees. Lens decentration was significantly and positively correlated with age(r=0.2401, p=0.016)and was negatively correlated with the ACD(r=−0.222, p=0.025). The lens tilt was correlated with decentration(r=0.451, p<0.001).
Conclusion:CASIA2 can measure the position of crystalline lens of cataract patients. The lens tilt and decentration increased with age and may be affected by the ocular length and ACD.
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