多施設による緑内障患者の治療実態調査2016年版—正常眼圧緑内障と原発開放隅角緑内障

Multi-institutional survey on normal-tension and primary open-angle glaucoma in 2016

要約　目的：正常眼圧緑内障（NTG）と原発開放隅角緑内障（POAG）患者の使用薬剤を調査する。

対象と方法：2016年3月7日〜13日に57施設に受診したNTGとPOAG患者の使用薬剤を調査した。

結果：薬剤数はPOAG（2.1±1.3剤）がNTG（1.5±1.0剤）より多かった。単剤例では両病型ともPG関連薬の処方が最も多かった。2剤使用例では，両病型ともPG/β配合剤の処方が最も多かった。

結論：PG関連薬は単剤処方例，PG/β配合剤は2剤使用例で第一選択となっていた。NTGとPOAGでは使用薬剤に差はなかった。

Abstract　Purpose：To report the current status of eyedrops for glaucoma.

Cases and Method：This survey was made on the modality of topical treatment for normal-tension glaucoma（NTG）and primary open-angle glaucoma（POAG）during one week in March 2016 in 57 institutions. Report was obtained on 4,288 patients comprising 1,839 males and 2,449 females. The age ranged from 7 to 102 years, average 68 years. Findings were compared with similar studies made in 2012.

Results：POAG patients were receiving an average of 2.1±1.3 eyedrops. NTG patients were receiving 1.5±1.0 eyedrops. The difference was significant（p＜0.0001）. Among medications used as monotherapy for NTG, prostaglandin was the most frequent（74.0％）. For POAG, prostaglandin was the most frequently used（80.2％）. When two medications were used, prostaglandin combined with beta-blockers was the most frequent.

Conclusion：Prostaglandin was the most frequently used as a whole either as monotherapy or combination of multiple medications. There were no difference in medication between NTG and POAG.