白内障術後の角膜内皮細胞減少率における偽落屑症候群の影響

Loss of corneal endothelial cells after cataract surgery in eyes with pseudoexfoliation syndrome

要約　目的：白内障術後角膜内皮細胞減少における偽落屑症候群（PE）の影響の報告。

対象と方法：白内障手術を行ったPEを有する86例106眼と，年齢をマッチさせたPEのない対照群76例98眼を対象とし，患者背景と内皮細胞減少率を群間比較した。

結果：PE群は非PE群と比較して術前後の内皮細胞密度が少なく，瞳孔径が小さく，緑内障が多く，手術時間が長く，瞳孔拡張手技が多く，術後フレア値が高値と，背景には有意差があったが，術後3か月における内皮細胞減少率はPE群2.9±5.9％，非PE群2.6±4.9％と有意差はなかった。

結論：白内障術後角膜内皮細胞減少にPEは影響しない。

Abstract　Purpose: To report the loss of corneal endothelial cells after cataract surgery in eyes with and without pseudoexfoliation syndrome（PE）.

Cases: This study was made on 106 eyes of 86 cases who had PE and who received cataract surgery during the past 3 years. Another series of 98 eyes of 76 cases who had no PE and who received cataract surgery served as control. Findings were compared 3 months after surgery.

Results: Eyes with PE showed significantly less endothelial cell density, smaller pupil diameter, higher incidence of glaucoma, longer duration of surgery, more need to mechanically dilate the pupil, and higher aqueous flare before and surgery when compared than eyes without PE. Corneal endothelial cell density decreased by 2.9±5.9％ in eyes with PE and by 2.6±4.9％ in eyes without PE three months after surgery. The difference was not significant.

Conclusion: No difference was present in the rate of corneal endothelial density loss between eyes with and without PE when evaluated 3 months after cataract surgery.