Comparison of outcome of subtenon and intravitreal injection of triamcinolone acetonide for diabetic macular edema Naoto Imadome 1 , Hiroshi Kunikata 2 , Shunichiro Asano 3 , Hideyuki Konno 1 , Takeshi Izumi 1 , Toru Nakazawa 2 1Dept of Ophthalmol, Kesennuma City Hosp 2Dept of Ophthalmol and Vis Sci, Tohoku Univ Grad Sch of Med 3Dept of Ophthalmol, Yamagata City Hosp Saiseikan pp.705-710
Published Date 2015/5/15
DOI https://doi.org/10.11477/mf.1410211339
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Abstract. Objective:To compare the effects of intravitreal triamcinolone acetonide(IVTA)and subTenon triamcinolone acetonide(STTA)injection for the treatment of diabetic macular edema(DME). Methods:In this retrospective series of 32 eyes of 25 patients with DME, 10 eyes underwent STTA(2011〜2012)and 22 eyes underwent IVTA(2013〜2014)injection. Improvement in visual acuity(VA), central retinal thickness(CRT)and intraocular pressure(IOP)were assessed during 6 months after single TA treatment. Results:There was significant reduction in CRT 2-5 months post-STTA(4 months)and 1-6 months post-IVTA(6 months). There was also significant improvement in VA 2-4 months post-STTA(3 months)and 1-3 months post-IVTA(3 months). There was significant elevation in IOP 1-2 months post-IVTA(2 months), but not post-STTA. The period of enough reduction of CRT(≦300μm)was correlated with VA improvement after STTA(r=0.57, p=0.04), but not after IVTA(r=0.05, p=0.24). Conclusion:The therapeutic effect of TA for DME was unsustainable. It is possible that a different type of DME has a different effect with TA treatment.

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