Outcome of microincision vitrectomy for idiopathic macular hole with or without triamcinolone acetonide Hiroko Kanazawa 1 , Hiroshi Kunikata 1 , Masayuki Yasuda 1 , Fumihiko Nitta 1 , Jiro Kinukawa 1 , Toshiaki Abe 1 , Toru Nakazawa 1 1Dept of Ophthalmol, Tohoku Univ Grad Sch of Med pp.1219-1224
Published Date 2012/8/15
DOI https://doi.org/10.11477/mf.1410104327
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Abstract. Purpose:To report the outcome of vitrectomy for idiopathic macular hole with or without simultaneous use of triamcinolone acetonide(TA). Cases and Method:This retrospective study was made on 47 eyes of 47 patients who received vitrectomy with peeling of premacular and inner limiting membrane in the past 12 months. The series comprised 25 males and 22 females. The age ranged from 44 to 81 years, average 64 years. Adjunctive TA was used in 25 eyes. Indocyanine green(ICG)was used with or without TA in 26 eyes. Thirty-three eyes received lens removal. Results:Visual acuity was better in eyes treated without TA and ICG than in eyes with TA alone(p<0.05). There was no difference in visual acuity between eyes treated with ICG alone, and with simultaneous TA and ICG. Intraocular pressure(IOP)was higher in eyes treated with TA than in those without(p<0.05). Retinal thickness 6 months after surgery was greater in eyes treated with TA(p<0.05). Conclusion:Adjunct use of TA during vitrectomy for macular hole influenced postoperative visual acuity, IOP and retinal thickness. This finding may be related to toxicity and inflammatory effect of TA.

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