Effects of flunarizine on primary open angle and low tension glaucomas Kunihiko Fujita 1 , Chiaki Negishi 1 , Tairo Kimura 1 , Rumiko Ishii 1 , Akira Nakajima 1 1Dept of Ophthalmol Juntendo Univ pp.865-868
Published Date 1989/5/15
DOI https://doi.org/10.11477/mf.1410210813
  • Abstract
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We evaluated the effect of flunarizine, an antical-cium agent, in 28 cases with primary open angle glaucoma (POAG) and 17 cases of low tension glaucoma (LTG). Eight cases dropped out after continuous administration of 10 mg flunarizine for one year. While the visual field or disc cuppingshowed temporary improvements in 6 out of 45 cases (13 %), the improvements were not apparent after one year of treatment. Side effects were observed in 14 out of 37 cases (37 %). They includ-ed parkinsonism, episodes of mental depression and extrapyramidal lesions. Females and senile subjects were more prone to develop side effects.

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