ぶどう膜炎患者の角膜内皮細胞変化について

Corneal endothelial exchanges of uveitis patients

　種々の時期におけるぶどう膜炎患者52例（74眼）のスペクラーマイクロスコープによる角膜内皮細胞面積を計測し，次の結果を得た．

（1）肉芽腫性虹彩炎では，50％の症例で，正常範囲より拡大した面積を示した．

（2）非肉芽腫性虹彩炎では，ほとんど正常範囲面積を示した．

（3）角膜中央部と下方部の面積差はなかった．

（4）豚脂様角膜後面沈着物付着部位付近の内皮細胞面積は拡大傾向を示した．

　これらより豚脂様角膜後面沈着物は角膜内皮細胞への影響因子として重要であると考えられた．

We evaluated the corneal endothelium in 74 eyes, 52 patients, with uveitis. The series included 33 eyes with nongranulomatous uveitis (serous iritis 17 eyes, Behget's disease 16 eyes) and 41 eyes with granulomatous uveitis (Harada's disease 8 eyes, ocular sarcoidosis 6 eyes, glaucomatocyclitic crises 9 eyes, herpes zoster iridocyclitis 7 eyes and others). We used contact type wide-field specularmicroscope in tne evaivation.

The mean endothelial cell size was larger than in control in 50% of cases with granulomatous uveitis The cell size in nongranulomatous iritis was the same as in control. There was no difference in the endothelial cell size between the central area and the posterior sector of the cornea. There was a tendency for the cell size to increase in the area with mutton fat deposits.

The findings seemed to indicate that the retrocor. neal mutton fat deposits exerts a major influence on the corneal endothelial cells.

Rinsho Ganka (Jpn J Clin Ophthalmol) 42(5) : 485-489, 1988