視神経乳頭黒色細胞腫の診断的ビトレクトミー

Diagnostic vitrectomy for melanocytoma of the optic disc

　右眼の視神経乳頭部に黒色腫瘍を有する61歳女性例を経験した．臨床的所見からは黒色細胞腫が疑われたが，硝子体中に浮遊する色素塊が存在したため，診断的ビトレクトミーを行った．組織標本中に多量の成熟したメラニン色素顆粒を持つ大型の細胞が認められ，またメラノサイトの集塊と思われる大量のメラニン顆粒の集簇も認められた事から，硝子体中の浮遊物は視神経乳頭黒色細胞腫由来の細胞群である事が推定された．

A 61-year old female presented with pigmented tumor of the optic disc in her right eye. The tumor occupied the nasal half of the disc and was not elevated. Visual functions were normal except for enlarged blind spot and irregular concentric con-striction of the visual field. Systemic and labora-tory findings were inconspicuous.

We detected a tiny pigmented mass floating in the vitreous of the right eye. We performed diag-nostic vitrectomy. Pathological studies showed large degenerated cells containing numerous andmature melanin granules in the cytoplasm. We diagnosed the pigmented floating mass as melanocytoma, presumably originating from the optic disc tumor.

Rinsho Ganka (Jpn J Clin Ophthalmol) 42(1) : 69-73, 1988