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(1)いわゆるEales病と診断された34例53眼について報告した.これは本邦における最多症例数で,経過観察し得た症例(その中,光凝固症例23例32眼,硝子体手術例4例4眼)は全例予後良好であった.早期に発見し,十分に光凝固を行えば良好な結果が得られるものと思われた.
(2) Eales病は網膜周辺部における血管閉塞性の疾患と考えられ,血液学的検査にてfibrinopeptide Aは正常範囲,fibrinopeptide Bβ15-42は明らかに高値を示す症例を認めた.
We evaluated 34 cases with peripheral retinal neovascularization diagnosed as Eales's disease. Argon laser photocoagulation was performed in 32 eyes (23 cases) and vitrectomy in 4 eyes (4 cases). No recurrent vitreous hemorrhage occurred in these treated eyes. The favorable prognosis was due to early detection of vascular abnormalities in the peripheral retina and sufficient argon laser photo-coagulation to nonperfused areas observed by re-peated fluorescein angiography. In some cases, neovascularization persisted after repeated photo-coagulation to the nonperfused areas. Direct photo-coagulation was applied to these persistent newly formed vessels. Hematological studies showed normal levels of fibrinopeptide A. An increased level of fibrinopeptide Bβ 15-42 was observed in some cases. This feature seemed to be possibly related to the pathogenesis of Eales's disease.
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