Clinicopathological study of Fuchs' heterochromic iridocyclitis Hiroshi Ohkuma 1 , Nobuko Kishimoto 1 , Masanobu Uyama 1 1Dep. of Ophthalmol., Kansai Med. Univ. pp.127-132
Published Date 1985/2/15
DOI https://doi.org/10.11477/mf.1410209326
  • Abstract
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We observed 12 cases of Fuchs' iridocyclitis during the past 5-year period. The ages ranged from 31 to 67 years. Both sexes were equally in-volved. The condition was unilateral in all cases.

No obvious heterochromia of the iris was seen in 6 of the 12 eyes. All the affected eyes, though, manifested atrophy of the iris : an important clini-cal sign at the diagnosis of this disorder.

Seven eyes were treated by cataract surgery with uneventful postsurgical course. Iris specimens were obtained from 8 eyes during surgery for cataract or glaucoma and were subjected to electron micro-scopic studies. All the eight specimens showed minimal lymphocyte and plasma cell infiltrations in the stroma and the perivascular space. Narrow-ing of vascular lumen or degenerative changes of stromal vessels were seen in 5 eyes.

While the pathogenesis of this syndrome is still far from clear, our findings point to the probable predominant role played by degenerative changes of iris vessels reflecting the disruption of blood-iris barrier.

Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.


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