眼球形状と水晶体形状の発達に対する定量的解析

Quantitative analysis of morphology of the eyeball and crystalline lens in infants and children

要約　目的：楕円フーリエ記述子を用いた，眼球形状と水晶体形状の相関関係の検討。対象と方法：1か月～6歳の27例27眼を対象とした。MRIのT2強調画像から，標準化楕円フーリエ記述子に基づいて眼球形状および水晶体形状を80個の数列として記述した。また，MRI画像から眼軸長，前房深度，水晶体厚を測定した。結果：年齢と，水晶体形状発達主成分（r＝－0.632，p＜0.001），眼球形状発達主成分（r＝－0.625，p＜0.001）とは有意に相関した。眼軸長と水晶体厚，眼球形状発達主成分とは相関がなかったが，水晶体形状発達主成分と眼球形状発達主成分とは有意に相関した（r＝0.563，p＝0.0018）。結論：眼球発達の過程では，眼球形状と水晶体形状に有意の相関がある。

Abstract.　Purpose：To report changes in the shape of eyeball and crystalline lens in children up to 6 years of age. Objects and Method：made on 27 eyes of 27 infants and children ranging from 1 month to 6 years of age,average 1.7 years. T2-weighted MRI images of the eyeball and crystalline lens were expressed as 80 sequences after processing by elliptic Fourier descriptors. MRI imaging was also used to measure the axial length,depth of the anterior chamber and the thickness of crystalline lens. Results：The age was positively correlated with the principal component of elliptic Fourier descriptors of crystalline lens（r＝－0.632,p＜0.001）and with that of eyeball（r＝－0.625,p＜0.001）. The axial length showed no correlation with the thickness of the lens or the principal component of elliptic Fourier descriptors of the eyeball. The principal component of elliptic Fourier descriptors of the lens and that of eyeball shape showed positive correlation（r＝0.563,p＝0.0018）. Conclusion：The shape of crystalline lens is significantly correlated with the shape and axial length of the eyeball in infants and children.