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Outcome of trabeculectomy with prior intravitreal bevacizumab injection for neovascular glaucoma Tetsuhiro Kawata 1 , Naoko Yamamoto 1 , Kyoko Matsushita 1 , Tomoko Naito 1 , Hiroshi Ohtsuki 1 , Makiko Takahashi 2 1Dept of Ophthalmol,Okayama Univ Grad Sch of Med,Dentistry and Pharmaceutical Sci 2Dept of Ophthalmol,Kasaoka Daiichi Hosp pp.1457-1460
Published Date 2009/9/15
DOI https://doi.org/10.11477/mf.1410102862
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Abstract. Purpose:To compare the outcome of trabeculectomy for neovascular glaucoma with or without prior intravitreal injection of bevacizumab. Cases and Method:We reviewed 26 eyes of 24 cases who received trabeculectomy during the past 39 months. Neovascular glaucoma was due to diabetic retinopathy 17 eyes,retinal vein occlusion 6 eyes,and others 3 eyes. Nine eyes received intravitreal bevacizumab one to 14 days before surgery. Results:Final intraocular pressure(IOP)averaged 11.0±1.4 mmHg in 9 eyes receiving bevacizumb and 9.0±1.4 mmHg in the other 17 eyes. When final IOP over 15 mmHg or additional treatment glaucoma was defined as death,rate of survival was 77.7% in 9 eyes receiving bevacizumab and 60.0% in the other 17 eyes 12 months after surgery. There was no significant difference between the two groups. Conclusion:Intravitreal injection of bevacizumab may decrease late complications of trabeculectomy and may induce early IOP control.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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