A型ボツリヌス毒素治療時のリドカインテープと冷却麻酔併用による鎮痛効果

Analgetic effect of ice pack and lidocaine tape during injection of botulinum A toxin

要約　目的：ボツリヌスA毒素の注射前に，局所冷却をリドカインテープ貼付に併用したときの鎮痛効果の報告。対象と方法：眼瞼けいれんに対してボツリヌスA毒素注射を行った9例を対象とした。全例が女性で，年齢は49～78歳（平均66歳）である。両眼のボツリヌスA毒素の注射予定部位にリドカインテープを30分間貼り，続いて片眼のみにアイスパックを2分間当てて冷却した。注射時の痛みを11段階で評価した。結果：主観的な痛みは，リドカインテープ単独では6.9，局所冷却を併用した側では2.8であり，59.4％の鎮痛軽減効果があった（p＝0.0003）。結論：ボツリヌスA毒素注射時に行うリドカインテープ貼付に局所冷却を併用すると，相乗的な鎮痛効果が得られる。

Abstract.　Purpose：To report the additive analgetic effect of application of ice pack during botulinum A toxin injection with application of lidocaine tape. Cases and Method：This prospective study was made on 9 patients who received botulinum A toxin injection for blepharospasm in both eyes. All were females with age ranging from 49 to 78 years,average 66 years. Lidocaine tape was patched for 30 minutes to the site of injection in both eyes. Ice pack was then applied for 2 minutes to one eye only. Pain during injection was evaluated in 11 numerical scales. Results：Pain during injection averaged 2.8 with additional application of ice pack and 6.9 without. Use of ice pack resulted in reduction of pain by 59.4％. The difference was significant（p＝0.0003）. Conclusion：Additional use of ice pack induced greater reduction in pain during injection of botulinum A toxin than analgesia with lidocaine tape alone.