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Evaluation of a rapid diagnostic kit, Capilia Adeno(R) Eye, for adenoviral conjunctivitis Kazuhiko Yoshida 1 , Masataka Akanuma 1 , Takeshi Ohguchi 1 , Kazuhiro Ohgami 1 , Yoshimori Asato 2 , Tsutomu Ohashi 3 , Jun Shoji 4 , Keiji Nerome 5 , Rikutarou Hinokuma 6 , Koki Aoki 1 , Shigeaki Ohno 1 1Dept of Ophthalmol and Vis Sci, Hokkaido Univ Grad Sch of Med 2Asato Eye Clin 3Ohashi Eye Cent 4Shoji Eye Clin 5Chubu Eye Clin 6Hinokuma Eye Clin pp.71-74
Published Date 2008/1/15
DOI https://doi.org/10.11477/mf.1410102114
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Abstract. Purpose:To evaluate a newly developed rapid diagnostic kit, Capilia Adeno(R) Eye, for adenoviral conjunctivitis. Cases and Method:This clinical study was made on 100 patients suspected of adenoviral conjunctivitis in 6 institutions. Conjunctival scrapings from each patient were subjected first to immunochromatography, Capilia Adeno(R) Eye, and then to polymerase chain reaction(PCR)to identify the adenovirus. Results:PCR showed adenovirus in 74 samples, of which 60(81%)were judged as positive by Capilia Adeno(R) Eye. PCR showed no adenovirus in the remaining 26 samples, all of which were also negative by Capilia Adeno(R) Eye. Sensitivity by Capilia Adeno(R) Eye was independent of serotype of adnovirus or severity of conjunctivitis. Findings by Capilia Adeno(R) Eye were positive in more than 80% of cases on day 2 or 3 of conjunctivitis. Conclusion:Capilia Adeno(R) Eye is useful in the rapid diagnosis of adenovirus conjunctivitis.


Copyright © 2008, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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