Rinsho Ganka Volume 60, Issue 10 (October 2006)

Outcome of photodynamic therapy for age-related macular degeneration Fumiko Murao 1 , Makoto Kajima 1 , Takeshi Naito 1 , Hiroshi Shiota 1 1Dept of Ophthalmol and Vis Neurosci,Inst of Health Biosci,The Univ of Tokushima Grad Sch pp.1795-1798
Published Date 2006/10/15
DOI https://doi.org/10.11477/mf.1410100953
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Abstract. Purpose:To report the outcome of photodynamic therapy for age-related macular degeneration. Cases and Method:This study was made on 22 eyes of 22 patients who received photodynamic therapy for age-related macular degeneration during a one-year period. The series comprised 15 males and 7 females. Their age averaged 69.6±9.0 years. As inclusion criteria,their corrected acuity was 0.5 or less and choroidal neovascularion was located posterior to the fovea. The visual acuity averaged 0.175. Diameter of submacular lesion averaged 3,660±927μm. Results:Visual acuity averaged 0.20 6 months after treatment. The difference from baseline was not significant(p=0.36). When expressed as logMAR,visual acuity improved by 0.2 or more in 9 eyes(41%),remained unchanged in 7(32%),and deteriorated by 0.2 or more in 6(27%). Hemorrhage from choroidal neovascularization developed in 1 eye. One case developed dermatitis. Conclusion:Photodynamic therapy is reasonably safe and effective for age-related macular degeneration.

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60巻10号 (2006年10月)
電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院