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Conservative Treatment for Lumbar Canal Stenosis. The Effect of Lipo PGE1 Yukihiro Matsuyama 1 , Yoshihito Sakai 1 , Shiro Imagama 1 , Zenya Ito 1 , Norimitsu Wakao 1 , Naoki Ishiguro 1 1Department of Orthopaedic Surgery, Nagoya University School of Medicine Keyword: リポPGE1 , lipo PGE1 , 腰部脊柱管狭窄症 , lumbar canal stenosis , 下肢閉塞性動脈硬化症 , peripheral arterial disease pp.667-674
Published Date 2009/7/25
DOI https://doi.org/10.11477/mf.1408101543
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 Objective:To investigate the prevalence of lumbar canal stenosis (LCS) with peripheral arterial disease (PAD) and identity the optimal method of diagnosing PAD. Background of Data:The number of cases of LCS with PAD has been increasing recently, although its exact prevalence is unknown. Results:PAD was noted in 6 (31.6%) of 19 patients with LCS. ABI and TBI were less invasive examination procedures, and the PAD detection rates were high. TBI was particularly, useful for detecting PAD. Even when the results of ABI were normal, TBI revealed abnormal findings in many patients. In LCS patients who did not respond to an oral limaprost alfadex preparation, a 2-week course of intravenous Lipo PGE1 relieved lumbar/lower limb pain and significantly improved the patients' quality of life. Response to Lipo PGE1 therapy can be evaluated 2 weeks after the start of treatment.


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電子版ISSN 1882-1286 印刷版ISSN 0557-0433 医学書院

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