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Variance in Effects of Subthalamic Nucleus Stimulation Ryoichi Okiyama 1 , Fusako Yokochi 1 , Makoto Taniguchi 2 , Hiroshi Takahashi 2 , Naomi Hasegawa 3 , Ikuma Hamada 3 1Department of Neurology, Tokyo Metropolitan Neurological Hospital 2Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital 3Department of Neurophysiology, Tokyo Metropolitan Institute for Neurological Science Keyword: Parkinson's disease , deep brain stimulation subthalamic nucleus pp.883-888
Published Date 2002/10/1
DOI https://doi.org/10.11477/mf.1406902013
  • Abstract
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Chronic stimulation of subthalamus nucleus (STN) is effective in treating severe motor fluctuation and levodopa induced dyskinesia as well as parkinsonian motor symptoms. The improvement of peak-dose/ diphasic dyskinesias of STN stimulation is considered to be due to the decrease in the daily dosage of anti-parkinsonian drugs. However one report pointed out that STN stimulation improved directly levodopa in-duced dyskinesia. Moreover the timing of the im-provement for levodopa induced dyskinesia is not yet obvious.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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