Brain and Nerve No to Shinkei Volume 49, Issue 3 (March 1997)

A Case of Vitamin B2 Deficiency with Broad Neurologic Disorders and Canities Hiroyuki Katsuoka 1 , Chigusa Watanabe 1 , Yasuyo Mimori 1 , Shigenobu Nakamura 1 1Third Department of Internal Medicine, Hiroshima University School of Medicine Keyword: vitamin B12 , dementia , canities , neuropathy pp.283-286
Published Date 1997/3/1
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The patient was a 48-year-old woman with gait disturbance as her initial symptom. Two years after the onset of the gait disturbance, she developed motor weakness and a sensory disturbance in her limbs, and dementia. On admission to our hospital, the patient's serum vitamin B12, and folic acid levels were low, and she was found to have normochromic anemia. She also had widespread coarse hair and canities was diagnosed. The patient's paresthesia resolved in response to injection of 500μg mecobalamin every other day, and the Hasegawa dementia scale score and the patient's hand grip strength improved.

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Brain and Nerve 脳と神経
49巻3号 (1997年3月)
電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院