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An Autopsy Case of Catastrophic Antiphospholipid Syndrome Presenting with Recurrent Multiple Cerebral Infarction Associated with Lung Cancer Hiroyuki Katsuoka 1 , Yasuyo Mimori 2 , Tatsuo Kohriyama 2 , Masahiro Higaki 1 , Takako Mitsuoka 2 , Akira Harada 1 , Shigenobu Nakamura 2 , Kiyoshi Yukiu 3 , Yukikazu Awaya 4 , Toshiyuki Fukuhara 5 1Department of Neurology, Hiroshima Prefectural Hospital 2Third Department of Internal Medicine , Hiroshima University School of Medicine 3Department of Neurosurgery, Hiroshima Prefectural Hospital 4Department of Respiratory Medicine, Hiroshima Prefectural Hospital 5Department of Pathology and Clinical Laboratory, Hiroshima Prefectural Hospital Keyword: antiphospholipid syndrome , lupus anticoagulant , anticardiolipin antibody , multiple cerebral infarction , lung cancer pp.64-69
Published Date 2000/1/1
DOI https://doi.org/10.11477/mf.1406901549
  • Abstract
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We reported an autopsy case of cerebral infarction with primary lung cancer. The patient was a 50-year-old man. Despite having been treated with warfarin potassium and ticlopidine hydrochloride, he relapsed cerebral infarction. His laboratory data on admission showed that lupus anticoagulant was positive, together with a high value of β-thromboglobulin, thrombin-an-tithrombin III complex, markers of platelet and coagu-lation activation, CEA and CA 19-9.


Copyright © 2000, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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