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Visualization of Brain Function Using MRI : MR Functional Brain Imaging Hiroyuki Watanabe 1 , Takeo Kuwabara 1 , Masaki Ohkubo 2 , Kunio Sakai 3 , Shoji Tsuji 1 , Tatsuhiko Yuasa 1,4 1Department of Neurology, Brain Research Institute, Niigata University 2Department of Radiological Technology, College for Biomedical Technology, Niigata University 3Department of Radiology, School of Medicine, Niigata University 4Department of Neurology, Tokyo Medical and Dental University Keyword: functional imaging , brain function , photic stimulation , visual cortex , MRI pp.941-944
Published Date 1993/10/1
DOI https://doi.org/10.11477/mf.1406900544
  • Abstract
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The effects of photic stimulation on the visual cortex of human brain were studied by means of gradient-echo magnetic resonance imaging (MRI) . Fast low-angle shot (FLASH) MRI was used to monitor changes in brain oxigenation in the human visual cortex during photic stimulation (PS) . Whole -body 1.5 T clinical MR system was used. Elevation of image intensity up to 2% was observed in pri-mary and associative visual cortex, corresponding to an increase of blood oxygenation in regions of increased neural activity. After the PS was switched off, the MR signal fell below the pre-PS baseline level, which may be understood as an displacement of the oxygen-hemoglobin dissociation curve (the Bohre effect).


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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