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A CASE OF SUBACUTE INCLUSION ENCEPHALITIS (Dawson) Takeshi SHINOHARA 1 , Tetsu KURAMAE 1 , Naohiko TAKAHATA 2 1The Department of Neurosurgery, Hokkaido University, School of Medicine 2The Department of Neuro-psychiatry, Hokkaido University, School of Medicine pp.375-380
Published Date 1969/4/1
DOI https://doi.org/10.11477/mf.1406202530
  • Abstract
  • Look Inside

1) This is a 5-year-old boy of subacute ence-phalitis (Dawson's inclusion encephalitis) confirmed by right occipital lobe biopsy.

2) The onset of illness was noted by loss of left visual acuity and impaired consciousness.

The neurological examination on admission revealed impaired consciousness (confusion grade II), loss of left visual acuity, absence of left light reflex, left extensor plantar reflex and hypotonia of all extre-mities.

The clinical course was characterized by progressive impairment of consciousness, ballismus-like move-ment of upper extremities, and alternate appearance of decorticate or decerebrate posture.

2) The cerebrospinal fluid was normal except for increased γ-glohuline on electrophoresis.

The complement fixation test and isolation of viru-ses from the cerebrospinal fluid and feces were negative.

4) The right occipital lobe biopsied on the 25th hospital day revealed as follow :

Macroscopically, the meninges and cerebral cortex were normal.

Microscopically, perivascular cellular infiltration, de-generation of nerve cells, proliferation of microglia and intranuclear inclusion bodies of Cowdry's A-type were demonstrated.

There was no hemorrhage or necrotic lesion.

5) This case was discussed comparing with other references.


Copyright © 1969, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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