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METASTATIC TUMORS OF THE BRAIN Shoji ISHIMORI 1 1Deparment of Surgery Division of Neurosurgery Keio University School of Medicine pp.757-764
Published Date 1967/8/1
DOI https://doi.org/10.11477/mf.1406202252
  • Abstract
  • Look Inside

From 1960 to 1965, 50 cases of metastatic brain tumors have been collected in the Keio University Hospital. During which time 365 cases of brain tu-mors have been operated and verified histologically. The primary origins of the metastasis were, pulmonary cancery 26, breast cancer 6, uterine cancer and cho-rionepithelioma 4, skin (melanoma & melanosarcoma) 2, esophageal and gastric cancers 2, pancreas 1, urin-ary bladder 1, hypernephroma 1, adrenal gland 1, semi-noma 1, rib cancer 1, reticulum cell sarcoma 1, ep-ipharynx tumor 1, and origin unknown 2.

The age distribution was from 16 years to 70 years old, and the location of the intracranial metastasis was, frontal lobe 12, parietal lobe 10, temporal lobe 9, occipital lobe 6, cerebellum 6, brain stem 2 and cranium and dura 5 cases.

The clinical symptoms were analysed and the most prominent symptoms were hemiplegia, mental distur-bances and Jacksonian seizures.

The diagnosis was made mostly by cerebral a-ngiography of bilateral carotid and vertebral arteries.

Upon these 50 cases, major craniotomy was done on 20 cases, decompression operation was done on 6 cases, and on the remaining 24 cases, no neurosurgical treatment was done because of poor clinical condition with multiple metastasis in the central nervous system as well as metastasis to other organs.

The survival period was longest in the cases of ma-jor craniotomy was done, and in those decompression operation and non-operated cases, the survival periods were much shorter than the operated cases.

As the result, it would be concluded that the cases of brain metastasis are pessimistic as for their prog-nosis, because the survival cases were only 6, all of them were operated on with the diagnosis of primary brain tumor before the origins had been identified.

However, if the brain metastasis is solitary and op-erable and the primary origin is resectable, the prog-nosis would be much better by means of surgery as well as radiation and anti-cancer medicine like MMC.

As for the radiation therapy, the linear accellerator seems to be most effective for the primary origin and brain metastasis.


Copyright © 1967, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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