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転移性脳腫瘍は癌や肉腫などの悪性腫瘍が脳に転移した病態である。脳転移は容易に神経機能の悪化を招き,患者のQOLを著しく低下させる。癌の治療成績の向上に伴い,脳転移のコントロールは一段と重要性が増している。近年の放射線療法や薬物療法の発展は転移性脳腫瘍の治療にパラダイムシフトを起こしつつある。本稿では近年のさまざまな治療の進歩によって転換期にある転移性脳腫瘍の臨床像について概説する。
Abstract
Metastatic brain tumors are malignant lesions that spread to the brain from a primary neoplasm such as cancer or sarcoma located in other body organs. Brain metastases tend to cause deterioration of neurological function and negatively affect patients quality of life. Control of brain metastases is important, following improved outcomes that are being observed in patients with cancer. Recent advances in radiotherapy and drug therapy have led to a paradigm shift in the treatment of metastatic brain tumors. In this article, we review the clinical characterization of metastatic brain tumors that has reached a turning point in oncology.
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