雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

High-dose Intravenous Immunoglobulin in the Treatment of Sensory Ataxic Neuropathy with Sjgren's Syndrome : A Case Report Yoshiharu Taguchi 1 , Shutaro Takashima 1 , Maiko Takata 1 , Nobuhiro Dougu 1 , Etsuko Asaoka 1 , Hiroshi Inoue 1 1The Second Department of Internal Medicine, Toyama Medical & Pharmaceutical University Keyword: sensory ataxic neuropathy , Sjögren's syndrome , IVIg treatment pp.421-424
Published Date 2004/5/1
DOI https://doi.org/10.11477/mf.1406100284
  • Abstract
  • Look Inside

 We report herein a case of sensory ataxic neuropathy with Sögren's syndrome(SS-SAN) who became dramatically improved in response to high-dose intravenous immunoglobulin treatment(IVIg). An 81-year-old man began to feel numbness in his hands and feet in August 2002. Because he became unsteady and could not do skillfull movement, he was admitted to our hospital in May 2003. On neurological examination, all tendon reflexes were absent. His vibratory and position senses were severely impaired to knees and elbows. Touch, temperature, and pinprick sensations were mildly disturbed in a glove-stocking distribution. Coordination was clumsy in all limbs because of sensory loss. He had gait ataxia with Romberg sign. Nerve conduction study revealed that sensory nerve action potentials were absent. He was diagnosed as having SS-SAN because Schirmer test, Saxon test and both SS-A and SS-B antibodies were positive. Thereafter, IVIg, 400mg/kg daily for 5 days, was administered. His sensory impairment began to improve 2 days after IVIg. Subsequently, he could walk steadily without ataxia. It is considered that IVIg may be an effective treatment for SS-SAN.

(Received : December 22, 2003)


Copyright © 2004, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

関連文献

もっと見る

文献を共有