気腫性肺嚢胞およびその周囲の局所肺機能

Regional Pulmonary Function in Intra-emphysematous Bulla and Peri-emphysematous Bulla

　我々はポジトロンCTにて気腫性肺嚢胞内および気腫性肺嚢胞周囲の局所肺胞気量および局所分時換気量を測定した．この研究の目的は，どのように気腫性肺嚢胞が発育するかを調べることである．

　対象は10例の気腫性肺嚢胞患者である．検査は被検者を背臥位にし，スパイロメーターとの閉鎖回路内に¹³Nガスを入れ反復呼吸を行わせ，回路内のRI活性が平衡状態になった時，平衡画像を撮像した．その後空気にてRIを洗い出しその間連続的に3フレームを撮像し，RIの活性の低下を一次指数関数に近似させることにより，V/V_Aを求めた．

We have measured regional alveolar volume and regional ventilation of emphysematous lesions and periemphysematous lesions with positron emission tomography and N-13 gas in 10 patients.

The purpose of the study was to investigate how emphysematous lesion develops. The subjects were all male (except one) who put on a mask in supine posi-tion, and were connected with a spirometer. We gave N-13 gas in this closed circuit and had the gas rebreathed by the subjects. After activity reached equilibrium in closed circuit, an equilibrium scan was made.