Postextrasystolic potentiation after total or partial coronary occlusion in dogs Hajime Yamazaki 1 , Shigetaka Noma 1 , Makoto Akaishi 1 , Shunnosuke Handa 1 , Yoshiro Nakamura 1 , Masato Tani 1 1Cardiopulmonary Division, Department of Medicine, School of Medicine, Keio University pp.799-803
Published Date 1985/6/15
DOI https://doi.org/10.11477/mf.1404204694
  • Abstract
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Postextrasystolic potentiation (PESP) is widely used to detect viable but ordinary poorly contrac-ting myocardium due to coronary artery disease. PESP following coronary artery occlusion was studied serially using pairs of ultrasonic crystals to measure epicardial (EPI) and endocardial (ENDO) contractions in ischemic and nonischemic areas of left ventricle in 12 dogs.

After five minutes of total coronary occlusion (6 dogs) and thereafter, systolic expansion developed and PESP did not occur in both ENDO and EPI of the ischemic area. In contrast, in the ischemic EPI and ENDO that were akinetic, PESP persisted even after 2 hrs following partial coronary occlusion (6 dogs). PESP changed little in EPI and ENDO of the nonischemic areas after either total or partial coronary occlusion. Thus, loss of PESP occurred rapidly in not only ENDO but EN, which has different vulnerability to ischemia, following total coronaly occlusion. PESP was retained in both ENDO and EPI for at least 2 hrs following partial coronary occlusion.

Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.


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