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Japanese

Modification of Hemodynamic Changes by Heart Rate Following Sublingual Administration of Nitroglycerin: Echocardiographic Study Kiyomitsu Kamei 1 , Yoshifusa Aizawa 1 , Akira Shibata 1 , Yoshimi Takeuchi 2 , Masako Ishii 3 1First Department of Internal Medicine, Niigata University 2Department of Thoracic Surgery, Tachikawa General Hospital 3Department of Laboratory Examination Sanno-cho Hospital pp.313-317
Published Date 1985/3/15
DOI https://doi.org/10.11477/mf.1404204620
  • Abstract
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The effects of nitroglycerin (NTG) on cardiacfunction can be evaluated by echocardiography. In this paper, we discussed the effects of NTG on cardiac function in two groups, one who had pacemaker implanted and their heart rate was fixed, and in other control group. Using echocardiography, left ventricular dimension was obtained in standard manner (Toshiba-SSH-11 A). Left ventricular end-diastolic dimension (Del) and end-systolic dimension (Ds) were obtained in each case and ejection fraction was calculated. After NTG (0.6 mg) sublingually, blood pressure decreased in two groups. Heart rate was fixed in the pacemaker group but increased significantly in control group. Dd and Ds were found to decrease only in the control group. Ejection fraction showed an increase in the majority of control group but it remained stationary. Heart rate change therefore may play a role in dimensional change and pumping function of heart after NTG.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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