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Evaluation of the SHAM method and proposal of the AM method in two compartmental analysis ofregional cerebral blood flow Hideo Mabe 1 , Masahiro Furuse 1 , Kiyonori Toyama 1 , Takehiko Nakaya 1 , Hiroji Kuchiwaki 1 , Atsushi Ikeyama 1 , Hirokazu Iguchi 2 , Fumio Matsunari 2 , Hiroshi Kuno 2 , Tomoyuki Kitano 2 1Department of Neurosurgery, Nagoya University School of Medicine 2Toyota Central Research & Development Laboratories, Inc. pp.741-745
Published Date 1979/7/15
DOI https://doi.org/10.11477/mf.1404203397
  • Abstract
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For calculating rCBF values from 133Xe clearance curves, the SHAM method for two compartmental analysis (Caprani, et al., 1975) was examined in 560 clearance curves in 21 patients with various brain diseases, such as cerebro-vascular disease, brain tumor and hydrocephalus.

In 60 curves of them (10.7%), the SHAM method failed to analyse the clearance curve, showing negative values in FW. In 37 of these cases (6.6%) the SHAM method was unable to calculate rCBF due to abnormal shape of the curves. The remaining 23 clearance curves (4.1 %) had a low counting rate below 1000 counts/ sec. and a blunt initial slope.


Copyright © 1979, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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