The Renal Response to Acutely Induced Hypercapnia and Anoxia

　1.　In normal dogs, receiving infusions　of sodium bicarbonate, acute hypercapnia　induced by breathing 10 per cent CO₂　re-sults in a significant increase in the rate　of reabsorption of bicarbonate from 2.37　to 3.69mEq per 100ccGFR, bearing close　relationship with the elevation of plasma　bicarbonate concentration.　These in-creased bicarbonate reabsorption was appa-rently higher than the maximal reabsorp-tion rate of bicarbonate in the control group　breathing room air　(2.5mEq／100ccGFR).