A Simple Treatment Strategy for Colorectal Serrated Lesions:Remove All Lesions≥6mm Daizen Hirata 1 , Wataru Sano 1 , Fumihiro Inoue 1 , Mineo Iwatate 1 , Santa Hattori 1 , Mikio Fujita 1 , Yasushi Sano 1 1Gastrointestinal Center, Sano Hospital, Kobe, Japan Keyword: 大腸鋸歯状病変 , 内視鏡治療 , SSL , SSL with dysplasia , HP pp.1573-1578
Published Date 2020/12/25
DOI https://doi.org/10.11477/mf.1403202203
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 Colorectal serrated lesions, especially SSLs(sessile serrated lesions)and traditional serrated adenomas are premalignant precursors to colorectal cancer. Unfortunately, the treatment strategy for colorectal serrated lesions remains unestablished in Japan. Our study shows that the probability of NICE or JNET type 1 lesions being SSLs substantially increased with the increase in lesion size and 6mm was observed to be the key threshold(≤5mm:0.7% ; 6-9mm:29.0% ; ≥10mm:70%). Moreover, the rate of dysplasia within SSLs also increases as the lesion size increases(≤5mm, 0% ; 6-9mm, 6.0% ; ≥10mm, 13.6%). Therefore, we recommend a standard of care that indicates all colorectal serrated lesions ≥6mm in size be removed. We are expecting that this simple treatment strategy will help decrease the morbidity and mortality rate associated with colorectal cancer in Japan.

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